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The purpose of this Funding Opportunity is to invite proposals for funding from private, non- profit microenterprise development organizations; microenterprise development programs run by State/Local/Tribal Governments; or Indian tribes interested in providing assistance and guidance to disadvantaged microentrepreneurs and/or microenterprise development organizations for the purposes stated in this Announcement.

DRL requests proposals to strengthen and develop democratic resilience, rule of law, freedom of speech and freedom of the press, and the defense of human rights in Europe through research, conferences, cultural engagements, and support for civil society to address national sovereignty, migration, censorship, and lawfare challenges in line with shared political philosophy, law, and our common Western civilizational heritage.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor announces an open competition for proposals for programs that will establish a new global program to counter transnational repression by strengthening coordination and building capacity among partner governments, law enforcement agencies, and civil society organizations. Transnational repression occurs when authoritarian regimes reach across international borders to silence, intimidate, harass, or harm members of diaspora communities, dissidents, journalists, and human rights defenders in other countries. These tactics threaten the safety and fundamental rights of individuals worldwide, including Americans and residents of partner countries.

DRL requests proposals to strengthen and develop democratic resilience, rule of law, freedom of speech and freedom of the press, and the defense of human rights in Europe through research, conferences, cultural engagements, and support for civil society to address national sovereignty, migration, censorship, and lawfare challenges in line with shared political philosophy, law, and our common Western civilizational heritage.

Summary: The fiscal year 2026 (FY26) Multiple Sclerosis Research Program (MSRP) Investigator-Initiated Research Award (IIRA) supports highly rigorous, high-impact research projects that have the potential to make an important contribution to Multiple Sclerosis (MS) research, patient care, and/or quality of life. All applications must address at least one of the FY26 MSRP IIRA focus areas. Research projects may focus on any phase of research, excluding clinical trials. The rationale for a research idea may be derived from laboratory discovery, clinical trial results, population-based studies, a clinician’s firsthand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to MS and the proposed research project.Distinctive Features: This funding mechanism includes two options: Established Investigator or New Investigator. The New Investigator option supports applicants early in their faculty appointments.

Summary: The fiscal year 2026 (FY26) Multiple Sclerosis Research Program (MSRP) Clinical Trial Award (CTA) supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of multiple sclerosis. All applications must address at least one of the FY26 MSRP CTA focus areas. Clinical trials may evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance and/or emerging approaches and technologies.Distinctive Features: The FY26 CTA offers two funding levels. The following are generalized descriptions of the scope of research appropriate for each funding level:• Funding Level 1 (CTA-FL1) supports small-scale, proof-of-principle clinical trials (e.g., pilot, first-in-human, phase 0) to demonstrate feasibility or inform the design of more advanced trials, or other clinical trials that are appropriate for this funding level. Preliminary data relevant to the proposed clinical trial are required.• Funding Level 2 (CTA-FL2) supports larger-scale clinical trials at phase 1 or phase 2 that seek to show preliminary evidence of safety or efficacy (i.e., benefit of clinical or paraclinical outcomes) in relevant patient populations. Clear description and justification should be provided, which could include, but is not limited to, the intervention type, trial duration, sample size, outcome measures, assessment tools and frequency of assessment. Preliminary data relevant to the proposed clinical trial in MS populations are required.For the purposes of this funding opportunity, Regulat...

Summary: The fiscal year 2026 (FY26) Multiple Sclerosis Research Program (MSRP) Exploration – Hypothesis Development Award (EHDA) supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the Multiple Sclerosis (MS) research field. The studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. All applications must address at least one of the FY26 MSRP EHDA focus areas. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. The presentation of preliminary and/or published data is not required.Distinctive Features: This funding mechanism includes two options: Established Investigator and New Investigator. The New Investigator option supports applicants early in their faculty appointments.

Summary: The fiscal year 2026 (FY26) Multiple Sclerosis Research Program (MSRP) Early Investigator Research Award (EIRA) supports Multiple Sclerosis-focused research opportunities for individuals in the early stages of their careers, under the guidance of one or more designated Mentors. All applications must address at least one of the FY26 MSRP EIRA focus areas.Distinctive Features: This opportunity allows for early-stage investigators to develop a research project, investigate a problem or question in MS research, and further their intellectual development as an MS researcher of the future. All application components for the EIRA are expected to be written by the Principal Investigator (PI), with appropriate direction from the Mentor(s).

The National Aeronautics and Space Administration (NASA) Headquarters has released the solicitation Early Stage Innovations for In Situ Resource Utilization (ESI26-ISRU), as an appendix to the Research and Technology Mission Directorate (RTMD) umbrella NASA Research Announcement (NRA) titled "Space Technology Research, Development, Demonstration, and Infusion 2026 (SpaceTech REDDI 2026).”. The solicitation is available by opening the NSPIRES homepage at https://nspires.nasaprs.com/, selecting “Open” under "Solicitations," and searching "Early Stage Innovations (ESI26)” under Keywords, or directly via https://solicitation.nasaprs.com/NNH26ZTR001N-26ESI_B7.      Through ESI, Space Technology Research Grants (STRG) Program within RTMD solicits proposals from U.S. institutions of higher education (IHEs) for innovative, early-stage space technology research of high priority to NASA. Proposals are sought on specific space technologies that are currently at low Technology Readiness Levels (TRLs). The solicitation exclusively seeks proposals that are primarily responsive to civil-space needs and use cases and not terrestrial and/or non-civil-space applications.    The solicitation exclusively seeks proposals that are responsive to the following topic: Lunar In Situ Resource Utilization Water Purification.    Only U.S. IHEs are eligible to submit proposals to this Appendix. The Principal Investigator (PI) must be either a tenured faculty member or an untenured faculty member on the tenure track from the proposing IHE. Teaming and collaboration are permitted, subject to the restricti...

The National Aeronautics and Space Administration (NASA) Headquarters has released the solicitation Early Stage Innovations (ESI), as an appendix to the Research and Technology Mission Directorate (RTMD) umbrella NASA Research Announcement (NRA) titled "Space Technology Research, Development, Demonstration, and Infusion 2026 (SpaceTech REDDI 2026).”. The solicitation is available by opening the NSPIRES homepage at https://nspires.nasaprs.com/, selecting “Open” under "Solicitations," and searching "Early Stage Innovations (ESI26)” under Keywords, or directly via https://solicitation.nasaprs.com/NNH26ZTR001N-26ESI_B2.    Through ESI26, Space Technology Research Grants (STRG) Program within RTMD solicits proposals from U.S. institutions of higher education (IHEs) for innovative, early-stage space technology research of high priority to NASA. Proposals are sought on specific space technologies that are currently at low Technology Readiness Levels (TRLs). The solicitation exclusively seeks proposals that are primarily responsive to civil-space needs and use cases and not terrestrial and/or non-civil-space applications.    The solicitation exclusively seeks proposals that are responsive to one of the following eight topics:  Acceleration of Computational Fluid Dynamics of High-Enthalpy Hypersonic Flows Using Advanced Numerics and Machine Learning   Advancements in Autonomous Maintenance and Manufacturing Technologies for the Moon and Mars  Computational Techniques for the Design and Characterization of Oxidation-Resistant Refractory Alloys for Aerospace Applications   Entry-Induc...

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Freedom of expression online faces threats globally from authoritarian governments employing sophisticated technology to restrict speech, control the flow of information, and chill dissenting voices. These challenges infringe on privacy; access to information; and the exercise of freedoms of expression, peaceful assembly, association, and religion or belief online. The misuse of commercial spyware is increasingly deployed by authoritarian governments and other digital threat actors to suppress dissent and restrict freedom of expression and privacy. Artificial Intelligence (AI) is now facilitating cyberattacks, lowering the barrier of entry for threat actors and improving their efficiency and effectiveness.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in submitting applications for a rapid response mechanism to support Track 2.0 style peacebuilding convenings in conflict-affected regions of strategic importance to the United States. This program will provide flexible, timely support for convening civil society actors, activists, journalists, and other key stakeholders who are essential to advancing and sustaining peace processes in priority regions including Armenia, Azerbaijan, Cambodia, Thailand, DRC, Rwanda, and other conflict affected regions of strategic importance.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor announces an open competition for organizations interested in submitting applications for projects that combat transnational repression in the Europe and Eurasia region.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in submitting applications for a rapid response mechanism to support Track 2.0 style peacebuilding convenings in conflict-affected regions of strategic importance to the United States. This program will provide flexible, timely support for convening civil society actors, activists, journalists, and other key stakeholders who are essential to advancing and sustaining peace processes in priority regions including Armenia, Azerbaijan, Cambodia, Thailand, DRC, Rwanda, and other conflict affected regions of strategic importance.

Freedom of expression online faces threats globally from authoritarian governments employing sophisticated technology to restrict speech, control the flow of information, and chill dissenting voices. These challenges infringe on privacy; access to information; and the exercise of freedoms of expression, peaceful assembly, association, and religion or belief online. The misuse of commercial spyware is increasingly deployed by authoritarian governments and other digital threat actors to suppress dissent and restrict freedom of expression and privacy. Artificial Intelligence (AI) is now facilitating cyberattacks, lowering the barrier of entry for threat actors and improving their efficiency and effectiveness.

The U.S. Department of Agriculture, Foreign Agricultural Service, announces this Notice of Funding Opportunity (NOFO) to support the E (Kika) de la Garza Emerging Markets Program (EMP) by issuing new awards. The purpose of this program is to develop, maintain, or expand markets for exports of United States agricultural commodities and to promote cooperation and exchange of information between agricultural institutions and agribusinesses in the United States and emerging markets. This opportunity is available to U.S. entities to achieve the purposes of this program by: (1) making assessments of food and rural business systems needs; (2) making recommendations on measures necessary to enhance the effectiveness of food and rural business systems, including potential reductions in trade barriers; and (3) identifying and carrying out specific opportunities and projects to enhance the effectiveness of food and rural business systems in emerging markets.

Under the Cooperator Program, USDA/FAS enters into agreements with nonprofit agricultural trade organizations (“Cooperators”) to share the costs of maintaining and developing foreign markets for United States agricultural commodities and products. Financial assistance under the Cooperator Program is made available on a competitive basis, and USDA/FAS endeavors to enter into agreements with eligible Cooperators to cover as broad an array of agricultural commodities as possible. All U.S. agricultural commodities, except tobacco, are eligible for consideration.

Under MAP, USDA/FAS enters into agreements with Participants to share the cost of certain marketing and promotion activities to expand exports of U.S. agricultural commodities. Financial assistance under the MAP is made available on a competitive basis, and USDA/FAS endeavors to enter into agreements with eligible Participants to cover as broad an array of agricultural commodities as possible. All U.S. agricultural commodities, except tobacco, are eligible for consideration.

The QSP is designed to encourage the development and expansion of export markets for U.S. agricultural commodities by assisting U.S. entities in providing commodity samples to potential foreign importers to promote a better understanding and appreciation for the high quality of U.S. agricultural commodities.

The TASC program is designed to assist U.S. organizations by providing funding for projects that seek to remove, resolve, or mitigate existing or potential sanitary, phytosanitary, or technical barriers that prohibit or threaten the export of U.S. specialty crops.

The U.S. Environmental Protection Agency (EPA) is soliciting applications under the authority of the Clean Water Act (CWA) section 104(b)(8) to provide Technical Assistance and Training for Rural, Small and Tribal Municipalities and Wastewater Treatment Systems. The program supports small, rural, and Tribal communities’ efforts to identify water challenges, develop plans, build technical, financial, and managerial capacity, comply with CWA requirements, and access water infrastructure funding.Through this Notice of Funding Opportunity under the Clean Water Act, EPA will achieve greater protection of public health and the environment through an increase in trained water sector personnel, access to funding and financing for wastewater treatment facilities, and Clean Water Act compliance. This action advances the Administration’s priorities, including to Make America Healthy Again, by improving water quality and reducing exposure risks, and enabling responsible economic growth for small, rural, and tribal communities through improved wastewater infrastructure. In partnership with States, Tribes, and local governments and grounded in sound science and the law, EPA will deliver cleaner water, stronger infrastructure, and long-term environmental stewardship for all Americans.The proposed activities support the Agency’s Powering the Great American Comeback Initiative’s Pillar 1: Clean Air, Land, and Water for Every American. Priority Areas identified in this opportunity are:(1) Technical assistance and training for rural, small, and Tribal municipalities for planning, developing a...

The U.S. Department of Agriculture, Foreign Agricultural Service, Fellowship Programs, announces this funding opportunity to support the Norman E. Borlaug International Agricultural Science and Technology Fellowship Program by issuing a new award. This opportunity is available to State cooperative institutions or other colleges and universities in the United States, as defined at 7 U.S.C. § 3103. This program is intended to support applied research, extension, and education collaborations between U.S. researchers and their foreign counterparts from selected emerging market economies.Benefits to the United States: This program makes America more prosperous by strengthening trade and expanding and developing new markets with current and potential trading partners.

The U.S. Department of Agriculture, Foreign Agricultural Service, Fellowship Programs, announces this funding opportunity to support the Cochran Fellowship Program by issuing a new award. This opportunity is available to State cooperative institutions or other colleges and universities in the United States, as defined at 7 U.S.C. § 3103. This program is intended to support applied research, extension, and education collaborations between U.S. researchers and their foreign counterparts from selected emerging market economies.Benefits to the United States:• This program makes America more prosperous by increasing American agricultural exports to new or expanded overseas markets.

Broadly, the objective is to develop partnerships to improve access to, and use of, heritage resources, and promote their educational, scientific, cultural, and recreational values in a manner that meets U.S. Department of the Interior priorities and Cultural Heritage and Paleontology Program goals. Individual projects shall meet one or more of the following objectives.Conduct studies, including inventory, excavation, records research, and collections-based research to improve the understanding of America"s natural and cultural history;Monitor at-risk heritage resources to track trends in condition and project effectiveness;Stabilize at-risk heritage resources;Train future cultural resource management practitioners and paleontologists through research projects, field schools and internships that highlight BLM resources;Assist with cultural heritage data and records management activities such as organizing, maintaining, and scanning site and survey records; creating, digitizing and maintaining geospatial data; and performing data entry;Preserve existing collections at recognized curation facilities through such activities as archival housing, stabilization or conservation;Broaden public access to museum collections;Promote engagement with Native American communities and foster partnerships with tribal governments and programs;Promote public engagement, learning opportunities, and conservation/preservation ethics through heritage resources education and outreach programs, events, and products;Develop and maintain historic sites with interpretive and educational potential.Part...