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TheParticulate and Multiphase Processesprogram is part of the Transport Phenomena cluster, which also includes 1) theCombustion and Fire Systemsprogram; 2) theFluid Dynamicsprogram; and 3) theThermal Transport Processesprogram. Thegoal of theParticulate and Multiphase Processesprogram is to support fundamental research on physico-chemical phenomena that govern particulate and multiphase systems, including flow of suspensions, drops and bubbles, granular and granular-fluid flows, behavior of micro- and nanostructured fluids, unique characteristics of active fluids, and self assembly/directed-assembly processes that involve particulates.The program encourages transformative research to improve our basic understanding of particulate and multiphase processes with emphasis on research that demonstrates how particle-scale phenomena affect the behavior and dynamics of larger-scale systems.Although proposed research should focus on fundamentals, a clear vision is required that anticipates how results could benefit important applications in advanced manufacturing, energy harvesting, transport in biological systems, biotechnology, or environmental sustainability.Collaborative and interdisciplinary proposals are encouraged, especially those that involve a combination of experiment with theory and/or modeling. Major research areas of interest in the program include: Multiphase flow phenomena:Dynamics ofparticle/bubble/droplet systems,behavior of structured fluids (colloids/ferro-fluids), granular flows, rheology of multiphase systems, unique characteristics of active fluids in novel ap...

The Interfacial Engineering program is part of the Chemical Process Systems cluster, which also includes: 1) the Catalysis program; 2) the Electrochemical Systems program; and 3) the Process Systems, Reaction Engineering, and Molecular Thermodynamics program. The goal of the Interfacial Engineering program is to support fundamental research on atomic- and molecular-scale interfacial phenomena and engineering of interfacial properties, processes, and materials. Fundamental understanding of the thermodynamic, kinetic, and transport properties of interfacial systems underpins improvements in chemical process efficiency and resource utilization. As such, proposed research should have a clear vision for how the results will translate to practice in or otherwise advance industrial chemical or biochemical processes. The program encourages proposals that present new approaches to long-standing challenges or address emerging research areas and technologies. Collaborative and interdisciplinary proposals are also encouraged, particularly those that involve a combination of experiment with theory or modeling. Major research areas of interest in the program include: Chemical separations: Design of scalable mass separating agents (for example, sorbents and membranes); field-induced separation processes that target a significant reduction in energy and/or materials requirements Biological separations: Downstream processing of biologically-derived chemicals, therapeutic proteins, and biologics for increased throughput and purity; engineering interfaces for molecular recognition Interfacial...

TheFluid Dynamicsprogram is part of the Transport Phenomena cluster, which also includes 1) theCombustion and Fire Systemsprogram; 2) theParticulate and Multiphase Processesprogram; and 3) theThermal Transport Processesprogram. TheFluid Dynamicsprogram supports fundamental research toward gaining an understanding of the physics of various fluid dynamics phenomena. Proposed research should contribute to basic scientific understanding via experiments, theoretical developments, and computational discovery. Major areas of interest and activity in the program include: Turbulence and transition: High Reynolds number experiments; large eddy simulation; direct numerical simulation; transition to turbulence; 3-D boundary layers; separated flows; multi-phase turbulent flows; flow control and drag reduction. High-speed boundary layer transition and turbulence at Mach numbers greater than 5 to understand modal and/or non-modal interactions leading to boundary layer transition and the ensuing developing and fully developed turbulent boundary layer flows.Combined experiments and simulations are encouraged. Bio-fluid physics:Bio-inspired flows; biological flows with emphasis on flow physics. Non-Newtonian fluid mechanics:Single-phase viscoelastic flows; solutions of macro-molecules. Bubble dynamics: Bubbles related to cavitation and/or drag reduction or impacting the fluid viscosity (locally) or manipulation of bubbles with external excitation (acoustofluidics). Microfluidics and nanofluidics: Micro-and nano-scale flow physics. Wind and ocean energy harvesting: Focused on fundamental flui...

The Communications, Circuits, and Sensing-Systems (CCSS) Program supports innovative research in circuit and system hardware and signal processing techniques. CCSS also supports system and network architectures for communications and sensing to enable the next-generation cyber-physical systems (CPS) that leverage computation, communication, and sensing integrated with physical domains. CCSS invests in micro- and nano-electromechanical systems (MEMS/NEMS), physical, chemical, and biological sensing systems, neurotechnologies, and communication & sensing circuits and systems. The goal is to create new complex and hybrid systems ranging from nano- to macro-scale with innovative engineering principles and solutions for a variety of applications including but not limited to healthcare, medicine, environmental and biological monitoring, communications, disaster mitigation, homeland security, intelligent transportation, manufacturing, energy, and smart buildings. CCSS encourages research proposals based on emerging technologies and applications for communications and sensing such as high-speed communications of terabits per second and beyond, sensing and imaging covering microwave to terahertz frequencies, personalized health monitoring and assistance, secured wireless connectivity and sensing for the Internet of Things, and dynamic-data-enabled autonomous systems through real-time sensing and learning. Areas managed by CCSS Program Directors (please contact Program Directors listed in the CCSS staff directory for areas of interest): RF Circuits and Antennas for Communications and...

NSF GRANTED supports innovative models of research enterprise administrative development and workforce training infrastructure that promote sustainable research capacity and opportunities for economic impactin U.S. organizations. The research enterprise, broadly defined, includes research development and administration, research analytics, technology transfer and commercialization, corporate relations/public-private partnerships, research integrity, compliance and security, research policy, administration of student research training, and research leadership. Strengthening and transforming this administrative infrastructure is necessary to fully utilize the Nation's research talent and capabilities and empower America's organizations that engage in or support research and its outcomes, to participate in a globally competitive research enterprise. Program Description Maintaining U.S. global leadership demands a research enterprise that is competitive, effective, sustainable and contributes to the Nation's economic growth goals. A strong national research enterprise relies on more than funding for the research itself. It also requires robust administrative support-and-service infrastructure, which is often unseen, yet includes critical components to ensure a competitive research environment regardless of organization or location. Research enterprise infrastructure enables the development of proposals and management of awards and supports research translation through technology transfer and public-private partnerships. Research compliance enables the security and integrity of....

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The Manufacturing Systems Integration (MSI) Program supports fundamental research addressing the opportunities and challenges that digital technologies present for the next industrial revolution, with particular emphasis on the digital integration of design and manufacturing within the larger life cycle ecosystem. Manufacturing Systems Integration proposals should address underlying principles and advances that are generalizable for globally competitive and world leading industries. Connectivity, automation, and secure collaboration are examples of areas that are integral to digital environments capable of supporting the innovation, realization and sustainment of manufactured products and systems in the value creation process. Fundamental generalizable research for manufacturing systems integration might include, for example: Digital representation, protocols, and/or processes for integration and collaboration in manufacturing systems (machines and/or humans) Intelligent self-organizing production systems Ease of use, interoperability and seamless integration of technologies, machines, and humans Service-oriented architectures and systems Data sets that are compatible and usable across platforms Reliable and secure communications within and across the manufacturing value chain Integration of distributed manufacturing systems across time and space, including incorporating both legacy and leading-edge equipment and technologies Methods for assessing the impact and value of externalities throughout the life cycle within the digital environment Interdisciplinary, convergent pro...

PLEASE FIND THE NOFO IN THE 'DOCUMENTS' SECTION OF THIS POST This opportunity has been updated as of May 11, 2026 Program Overview: EDA has authority to provide grants to meet the full range of communities’ and regions’ economic development needs from planning and technical assistance to construction of infrastructure. These grants are made through a series of Notices of Funding Opportunity (NOFOs) that can be found on EDA’s website at https://www.eda.gov/funding/funding-opportunities and are designed to support the economic development activities most useful to a community based on its needs and circumstances. EDA funds community or regionally generated ideas and assists communities to advance to the next level of economic development. This NOFO sets out EDA’s application submission and review procedures for two of EDA’s core economic development programs authorized under the Public Works and Economic Development Act of 1965, as amended (42 U.S.C. § 3121 et seq.) (PWEDA): (1) Public Works and Economic Development Facilities (Public Works) and (2) Economic Adjustment Assistance (EAA). EDA supports bottom-up strategies that build on regional assets to spur economic growth and resiliency. EDA encourages its grantees throughout the country to develop initiatives that present new ideas and creative approaches to advance economic prosperity in distressed communities. Through this NOFO EDA intends to advance general economic development in accordance with EDA’s investment priorities, which can be found on EDA's website here: Investment Priorities | U.S. Economic Development Admi...

TheElectrochemical Systemsprogram is part of the Chemical Process Systems cluster, which also includes: 1) theCatalysisprogram; 2) theInterfacial Engineeringprogram; and 3) theProcess Systems, Reaction Engineering, and Molecular Thermodynamicsprogram. The goal of theElectrochemical Systemsprogram is to support fundamental engineering science research that will enable innovative processes involving electrochemistry or photochemistry for the sustainable production of electricity, fuels, chemicals, and other specialty and commodity products. Processes utilizing electrochemistry or photochemistry for sustainable energy and chemical production must be scalable, environmentally benign, reduce greenhouse gas production, and utilize renewable resources. Research projects that stress fundamental understanding of phenomena that directly impact key barriers to improved system or component-level performance (for example, energy efficiency, product yield, process intensification) are encouraged. Processes for energy storage should address fundamental research barriers for renewable electricity storage applications, for transport propulsion, or for other applications that could have impact towards climate change mitigation. For projects concerning energy storage materials, proposals should involve testable hypotheses that involve device or component performance characteristics that are tied to fundamental understanding of transport, kinetics, or thermodynamics. Advanced chemistries beyond lithium-ion are encouraged. Proposed research on processes utilizing electrochemistry or photochemis...

TheEnvironmental Sustainability program is part of theEnvironmental Engineering and Sustainabilitycluster together with 1) theEnvironmental Engineeringprogram and 2) theNanoscale Interactionsprogram. The goal of theEnvironmental Sustainabilityprogram is to promote sustainable engineered systems that support human well-being and that are also compatible with sustaining natural (environmental) systems. These systems provide ecological services vital for human survival. Research efforts supported by the program typically consider long time horizons and may incorporate contributions from the social sciences and ethics. The program supports engineering research that seeks to balance society's need to provide ecological protection and maintain stable economic conditions. There are five principal general research areas that are supported. Circular Bioeconomy Engineering:This area includes research that enables sustainable societal use of food, energy, water, nitrogen, phosphorus, and materials, with the reduction and eventual elimination of fossil fuel combustion that lacks carbon capture. The program encourages research that helps build the raw material basis for the functioning of society principally on biomass, drawing heavily on sustainable agriculture and forestry. Additionally, material flows must reduce or preferably eliminate waste, with an emphasis on closed-loop or “circular” processing. Industrial ecology:Topics of interest include advancements in modeling such as life cycle assessment, materials flow analysis, net energy analysis, input/output economic models, and nove...

TheBiophotonicsprogram is part of the Engineering Biology and Health cluster, which also includes: 1) theBiosensingprogram; 2) theCellular and Biochemical Engineeringprogram; 3) theDisability and Rehabilitation Engineeringprogram; and 4) theEngineering of Biomedical Systemsprogram. The goal of theBiophotonicsprogram is to explore the research frontiers in photonics principles, engineering and technology that are relevant for critical problems in fields of medicine, biology and biotechnology. Fundamental engineering research and innovation in photonics is required to lay the foundations for new technologies beyond those that are mature and ready for application in medical diagnostics and therapies. Advances are needed in nanophotonics, optogenetics, contrast and targeting agents, ultra-thin probes, wide field imaging, and rapid biomarker screening. Low cost and minimally invasive medical diagnostics and therapies are key motivating application goals. Research topics in this program include: Imaging in the second near infrared window:Research that advances medical applications of biophotonics in the second near-infrared window (NIR-II: 1,000-1,700 nm) in which biological tissues are transparent up to several centimeters in depth, making this spectral window ideal for deep tissue imaging. Macromolecule markers: Innovative methods for labeling of macromolecules. Novel compositions of matter. Methods of fabrication of multicolor probes that could be used for marking and detection of specific pathological cells.Pushing the envelope of optical sensing to the limits of detection, r...

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The Energy, Power, Control, andNetworks (EPCN) Program supports innovative research in modeling, optimization, learning, adaptation, and control of networked multi-agent systems, higher-level decision making, and dynamic resource allocation, as well as risk management in the presence of uncertainty, sub-system failures, and stochastic disturbances. EPCN also invests in novel machine learning algorithms and analysis, adaptive dynamic programming, brain-like networked architectures performing real-time learning, and neuromorphic engineering. EPCN’s goal is to encourage research on emerging technologies and applications including energy, transportation, robotics, and biomedical devices & systems. EPCN also emphasizes electric power systems, including generation, transmission, storage, and integration of renewable energy sources into the grid; power electronics and drives; battery management systems; hybrid and electric vehicles; and understanding of the interplay of power systems with associated regulatory & economic structures and with consumer behavior. Areas managed by Program Directors (please contact Program Directors listed in the EPCN staff directory for areas of interest): Control Systems Distributed Control and Optimization Networked Multi-Agent Systems Stochastic, Hybrid, Nonlinear Systems Dynamic Data-Enabled Learning, Decision and Control Cyber-Physical Control Systems Applications (Biomedical, Transportation, Robotics) Energy and Power Systems Solar, Wind, and Storage Devices Integration with the Grid Monitoring, Protection and Resilient Operation of Grid Power Gr...

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The Economics program supports research designed to improve the understanding of the processes and institutions of the U.S. economy and of the world system of which it is a part. This program also strengthens both empirical and theoretical economic analysis as well as the methods for rigorous research on economic behavior. It supports research in almost every area of economics, including econometrics, economic history, environmental economics, finance, industrial organization, international economics, labor economics, macroeconomics, mathematical economics, and public finance. The Economics program welcomes proposals for individual or multi-investigator research projects, doctoral dissertation improvement awards, conferences, symposia, experimental research, data collection and dissemination, computer equipment and other instrumentation, and research experience for undergraduates. The program places a high priority on interdisciplinary research. Investigators are encouraged to submit proposals of joint interest to the Economics Program and other NSF programs and NSF initiative areas. The program places a high priority on broadening participation and encourages proposals from groups and regions that traditionally have not participated fully in science, mathematics, and engineering. The program also funds conferences and interdisciplinary research that strengthens links among economics and the other social and behavioral sciences as well as mathematics and statistics. The Doctoral Dissertation Research Improvement Grants (DDRIG) funding opportunity is designed to improve the....

Synopsis TheCellular and Biochemical Engineering(CBE)program is part of theEngineering Biology and Healthcluster, which also includes: 1) theBiophotonicsprogram; 2) theBiosensingprogram; 3) theDisability and Rehabilitation Engineeringprogram; and 4) theEngineering of Biomedical Systemsprogram. TheCellular and Biochemical Engineeringprogram supports fundamental engineering research that advances understanding of cellular andbiomolecular processes. CBE-funded research may lead to the development of enabling technology for advanced biomanufacturing of therapeutic cells, biochemicals, and biopharmaceuticals, and for otherbiotechnology industrie. The program encourages highly innovative and potentially transformative engineering research leading to novel bioprocessing and biomanufacturing approaches. Fundamental to many CBE research projects is the understanding of how biomolecules, subcellular systems, cells, and cell populations interact, and how those interactions lead to changes in structure, function, and behavior. A quantitative treatment of problems related to biological processes is considered vital to successful research projects in the CBE program. Major areas of interest for the program include: Metabolic engineering and synthetic biology for biomanufacturing, The design of synthetic metabolic components and synthetic cells, Microbiome structure, function, maintenance, and design, Protein and enzyme engineering, and Design of integrated chemoenzymatic systems. The CBE program also encourages proposals that effectively integrate knowledge and practices from different d...

The Catalysis program is part of the Chemical Process Systems cluster, which also includes: 1) the Electrochemical Systems program; 2) the Interfacial Engineering program; and 3) the Process Systems, Reaction Engineering, and Molecular Thermodynamics program. The goals of the Catalysis program are to increase fundamental understanding in catalytic engineering science and to advance the development of catalysts and catalytic reactions that are beneficial to society. Research should focus on critical challenges and opportunities in both new and proven catalysis technologies. Areas of emphasis may include novel catalyst compositions, structures, operating environment, data science tools, theory, and modeling – preferably in various combinations as dictated by the specific reaction and related knowledge and technology gaps. Target applications include fuels, specialty and bulk chemicals, environmental catalysis, biomass conversion to fuels and chemicals, greenhouse gas mitigation, recycling of waste materials, generation of solar hydrogen, as well as efficient routes to energy utilization. Heterogeneous catalysis represents the main thrust of the program. Proposals related to both gas-solid and liquid-solid heterogeneous catalysis are welcome, as are proposals that incorporate concepts from homogeneous catalysis. Recent research trends have highlighted the need for evaluation of catalyst performance and properties under working conditions, especially as supported by advanced in situ and in operando characterization methods. Catalyst synthesizability and stability present additi...

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TheEngineering of Biomedical Systemsprogram is part of the Engineering Biology and Health cluster, which also includes: 1) theBiophotonicsprogram; 2) theBiosensingprogram; 3) theCellular and Biochemical Engineeringprogram; and 4) theDisability and Rehabilitation Engineeringprogram. The goal of theEngineering of Biomedical Systems(EBMS) program is to provide opportunities for fundamental and transformative research projects that integrate engineering and life sciences to solve biomedical problems and serve humanity in the long term. Projects are expected to use an engineering framework (for example, design or modeling) that supports increased understanding of physiological or pathophysiological processes. Projects must include objectives that advance both engineering and biomedical sciences. Projects may include: methods, models, and enabling tools applied to understand or control living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; or new approaches to the design of systems that include both living and non-living components for eventual medical use in the long term. TheEBMS programsupports fundamental and transformative research in the following areas of biomedical engineering: Developmentof validated models (living or computational) of healthy and pathological tissues and organ systems that can support improved fundamental understanding of these systems or that could be applied in the future for development and testing of medical interventions; Designand validation of systems that integrate living and non-living c...