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Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:The scientific and clinical communities make effective use of state-of-the-art knowledge, data, technologies, tools, methods, best practices, and trainings to underpin and complement the development of innovative interventions aimed at more effective treatments for neurodegenerative diseases.The scientific and clinical communities benefit from the exchange of data, knowledge and best practices, thereby strengthening their collaboration in the EU, the Associated Countries and beyond.The scientific and clinical communities make wide use of...

Expected Outcome:Projects are expected to contribute to all of the following outcomes:Development of approaches, tools and methods, on how and where to restore, increase and maintain urban green space and tree canopy cover to achieve the greatest positive impacts - on climate mitigation, adaptation and resilience, biodiversity, soil, air and water quality, quality of life, and human health.Uptake and deployment of solutions to map, restore, increase and maintain urban green space and tree canopy cover, via pilot sites in lead cities, including along urban transport networks[1].Monitoring, evaluation and assessment of the environmental, economic, social and health impacts of the solutions deployed in pilot sites, including co-benefits and trade-offs.Dissemination of results to follower cities and relevant target groups in other countries and cities. Scope: To address the expected outcomes...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Healthcare professionals dispose of diagnostic tools at the point of care that accelerate therapeutic decision making.Patients benefit from fast and accurate diagnosis leading to improved health outcomes.Thanks to more efficient diagnosis, health systems will get better evidence for disease control and prevention strategies. Scope:Point-of-Care (PoC) medical testing has made great technical progress (e.g. improved extraction, microfluidics, miniaturisation, and data processing techniques) with PoC test accurac...

Expected Outcome:Projects are expected to contribute to all of the following outcomes:Cities and regions are equipped with innovative practices for urban wastewater management, adapted to climate change, taking into account: energy efficiency, energy and secondary raw material recovery and water reuse, including opportunities for renewable energy generation and secondary resource production, implemented at city and regional level.Treatment infrastructures and management solutions are deployed and upscaled for water, storm water and wastewater in cities and regions, with positive effects on climate adaptation, biodiversity, air and water pollution reduction, resource valorisation and energy efficiency.Knowledge is disseminated about innovative practices, governance and business models for integrated (waste)water management, in the context of climate change among relevant stakeholder group...

Expected Outcome:Successful proposals should support the recovery, resilience, and EU integration of Ukraine’s forest sector, addressing the compounded impacts of climate change and Russia’s war of aggression.Project results are expected to contribute to all of the following expected outcomes:Ukrainian decision-makers and policymakers gain access to robust scientific data, tools, and methodologies for developing and implementing evidence-based policies that are aligned with EU forest-related policies;recovery, restoration, sustainable management and development of Ukraine’s war-affected forests through improved governance, enhanced institutional capacity, and the implementation of sustainable forest management practices that address the impacts of climate change, biodiversity loss and Russian invasion;strengthened Ukrainian forest research and education systems, providing a solid evidenc...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:the capacities and integrated governance of researchers, decision-makers, practitioners, local communities and other stakeholders to effectively collaborate to prevent, eradicate or manage invasive alien species (IAS) are enhanced;native ecosystems are better protected, leading to improved resilience and continuous provision of ecosystem services including for climate mitigation and adaptation. Scope:Invasive alien species are one of the five main direct drivers of biodiversity loss. Besides inflicting major damage to nature and the economy, many invasive alien species also facilitate the outbreak and spread of infectious diseases, posing a threat to humans and native wildlife. The rate of new introductions of invasive alien species has increased in recent years. Without effective contro...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:all relevant stakeholders, including consumers, economic and social economy operators and waste managers, have an improved understanding of the technical, environmental, economic and social challenges and benefits to circularity in the footwear industry;economic operators and waste managers are provided with evidence-based, innovative, cost-effective, and scalable solutions that improve the management of end-of-life footwear products, valorise post-consumer footwear waste materials and increase the circularity of the value chain;consumers have access to user-friendly solutions to correctly dispose of end-of-life footwear, thus reducing landfill, improving sustainability practices, supporting them in making more conscious choices, and contributing to climate change mitigation and adaptati...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:the efficiency and competitiveness of the organic crop breeding sector are boosted by providing organic breeders with a comprehensive toolbox to develop varieties specifically adapted to intercropping and suitable for organic production;an improved understanding of key target traits for developing varieties adapted to intercropping farming systems is available to researchers and breeders, benefiting all agricultural systems;the foundation for the development of future crop varieties that enhance benefits derived by intercropping, such as improved pest/weed management, increased nutrient and water use efficiency, improved pollination, improved soil fertility, reduced soil erosion and nutrient leaching, and enhanced productivity, is established. Scope:Plant breeding has focused on maximisi...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:monitoring, reporting and verification (MRV) of air pollutants at farm level is improved;human health and environment (including biodiversity) benefit from reduced impacts of air pollution from agriculture;EU policies preventing and reducing air pollution are supported with more comprehensive, harmonised and accurate scientific evidence, tools and methods to estimate the emissions;farmers, advisors and other stakeholders acquire new and better knowledge, technologies and practices to reduce certain air pollutants from agriculture. Scope:EU agriculture contributes substantially to air pollution through various emissions. Additional efforts are needed in the sector to help reducing the impact on human health and the environment, including biodiversity. To promote the uptake of measures at...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes:society and decision-makers are provided with enhanced governance frameworks that integrate knowledge across ecosystems (terrestrial, freshwater and marine) and/or societal challenges, helping overcome institutional barriers, power asymmetries, and policy fragmentation to accelerate transformative change towards a nature positive economy and support EU climate goals;practitioners and public authorities co-create and have access to living labs as innovation hubs for testing, and scaling both governance and socio-economic models that integrate diverse knowledge systems, actively engage stakeholders and support bottom-up and participatory approaches. Scope:As nature positive actions gain momentum and biodiversity is increasingly integrated into policies, it is essential to ensure governance fr...

Expected Outcome: Project results are expected to contribute to all the following expected outcomes:enhanced capacity of private and public stakeholders to increase resource efficiency in collecting, processing and using primary and secondary biomass, ensuring that ecosystems and biodiversity are protected and restored, emissions of greenhouse gases and pollutants reduced, and human needs for biomass satisfied in sufficient and fair way, including food security;increased environmental, social and economic value added from the various uses of biomass, including bio-waste, e.g. food losses and food waste;reduction of greenhouse gas emissions and (air, water and soil) pollution, due to avoiding landfilling and incineration of bio-waste;demonstrated environmental, social and economic and social benefits for the municipalities involved in the collection and provision of bio-waste. Scope:Succe...

Expected Outcome:Successful proposals under this topic should contribute to the objectives of the EU Carbon Removals and Carbon Farming Certification (CRCF) Regulation and the Clean Industrial Deal, allowing industrial operators to use a sustainable carbon source as feedstock. They should facilitate innovators to scale up promising solutions in scope of the Strategy for European Life Sciences and the Biotech Act, also supporting the implementation of the EU Startup and Scaleup Strategy as well as the EU strategy on research and technology infrastructure.Project results are expected to contribute to all of the following expected outcomes:innovative and improved purification and conversion of gaseous carbon is developed and scaled up to provide feedstock for industrial processes promoting circularity and climate neutrality;advanced industries – applying life sciences technologies and biote...

Expected Outcome:Project results are expected to contribute driving the innovation of public authorities and industrial operators confronted with the Biocidal products regulation (EC) No 528/2012, within the 'safe and sustainable by design' framework. The outcomes should support the goals of the Commission communication on: Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU, of the EU Startup and Scaleup Strategy, of the Strategy for European Life Sciences and of the new EU bioeconomy strategy.Project results are expected to contribute to all of the following expected outcomes:innovation in bio-based and natural substances brings safer alternatives to hazardous substances contained in biocidal products, with decreased risk on human health and biodiversity, including pollinators;safe, sustainable and effective solutions are developed and tested for the...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:activities of protection and restoration of ecosystems by stakeholders become easier and more effective;conditions to scale up the implementation of the EU Nature Restoration Regulation by stakeholders are improved, thus improving ecosystem services including for climate mitigation and adaptation. Scope:Ecosystem restoration strategies for nature restoration and climate change mitigation require a coordinated and coherent set of human interventions and management practices (e.g. temporal protection of plants or removing invasive species, including their seeds) for which there is usually no dedicated mean like specific machinery, equipment or other technical innovations (like for example specific lures for invasive alien species). The most common practice is the use of agricultural machin...

Expected Outcome:The successful proposal funded under this topic will provide guidelines to industrial operators as well as administrators for contributing to the objectives of the Industrial and Livestock Rearing Emissions Directive, the Clean Industrial Deal and the Zero-pollution Action Plan, addressing technical goals in the scope of the Communication on boosting biotechnology and biomanufacturing in the EU and in the new EU bioeconomy strategy.Project results are expected to contribute to all of the following expected outcomes:innovative circular industrial bio-based systems – including biotechnologies and biomanufacturing – within the EU bioeconomy are deployed to decrease the environmental footprint of industries, not harm biodiversity and address climate neutrality. Scope:Industrial bio-based systems – made by the supply chain of bio-based feedstock and the industrial value chain...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes, driving transformative change for biodiversity and nature positive economic practices:overall, the economic case for biodiversity protection, restoration, sustainable use and the delivery of ecosystem services upon which all life depends, is strengthened including through robust assessments of the cost of inaction;businesses are better able to mainstream biodiversity considerations in decision-making, fostering transformative business models that enhance inclusion for biodiversity, particularly for start-ups and SMEs, including nature-based enterprises[1]. Leveraging synergies in business action on climate to strengthen overall resilience also needs to be considered;policy and decision makers benefit from improved knowledge to drive transformative policy including fiscal reforms to align e...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:advancing robust, policy-relevant ecosystem assessment, nature protection and restoration planning activities, and biodiversity trend prediction based on fit for purpose data, thus supporting EU biodiversity and climate objectives;strengthened capacity of researchers, practitioners and decision-makers to improve biodiversity monitoring practices and address knowledge gaps via the integration of data and observations across sensors and platforms, ranging from omics-based data (genomic, transcriptomic, metabolomic), various in-situ to satellite-based Earth observation data;enhanced usability of in-situ datasets as training and validation resources for statistical, machine learning and advanced AI-based approaches, in support of applications such as habitat classification, ecosystem mapping...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:material and product manufacturers apply relevant ecodesign, including design for circularity and design for recycling principles in developing and manufacturing products that contribute significantly to EU climate and through reduction of emissions and resource extraction to biodiversity goals, zero pollution, water resilience, circular economy, as well as open strategic autonomy;consumers benefit from more sustainable and circular products, i.e. durable, reliable, reusable, reparable, upgradable, recyclable products including increased recycled content. Scope:Electrical and electronic equipment continues to be one of the fastest growing waste streams in the EU, with current annual growth rates of 2%. It is estimated that less than 40% of electronic waste is collected in the EU.[1] Valu...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes:effective scientific support is provided by the Science Service for Biodiversity to all levels of policymaking related to biodiversity, through the European Commission’s Knowledge Centre for Biodiversity (KCBD); in particular, the coordination of answering ad hoc policy requests related to biodiversity through the mobilisation of the EU-funded scientific community, in collaboration with the KCBD, is expected;enhanced science-policy support and knowledge transfer from EU-funded R&I projects to the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) and the Convention on Biological Diversity (CBD) are ensured;a strengthened, multi-stakeholder knowledge and dialogue platform promotes biodiversity knowledge and the uptake and scaling of nature-based solution...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:European industry’s competitiveness, decarbonisation, and strategic autonomy are enhanced through the development and deployment of safe, sustainable, circular and bio-based value chains;improved climate change adaptation and mitigation and overall environmental sustainability, as well as higher resource efficiency, through application of biotechnologies and industrial symbiosis, and recovery of biological materials, water and energy. Scope:The projects under this topic are relevant to the EU policies related to the Commission communication on: Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU, the Life Sciences Strategy, the EU Biotech Act, Clean Industrial Deal and the SME Strategy. It also contributes to the Start-ups and Scale-ups strategy. Synerg...

Expected Outcome:Project results are expected to contribute to all of the following outcomes:  public authorities obtain access to enhanced and innovative modelling capabilities to support air quality planning at various policy levels in a coherent way;society benefits from improved governance processes and effective air quality planning strategies, aiming at mitigating air pollution and reducing population exposure, as well as from far more targeted air pollution alerts;public authorities, including EU policy-makers and the EEA, receive faster, more comprehensive scientific evidence and tools, enabling more effective EU air quality policy implementation and providing citizens with reliable, detailed information and peak pollution warnings to reduce health impacts. Scope:The air we breathe is often polluted, which can lead to serious health problems and even premature death. To address t...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:material and product manufacturers apply ecodesign principles in developing and manufacturing products that are safe and contribute significantly to EU climate, zero pollution, circular economy, and biodiversity goals, e.g., through biodiversity-enhancing circular design;consumers and professionals benefit from more sustainable and circular products, i.e. durable, safe, reliable, reusable, reparable, upgradable, recyclable products including increased recycled content. Scope:Construction is one of the most resource-intensive sectors of the economy. The construction sector is responsible for almost 39% of the EU’s total waste generation.[1] Greenhouse gas emissions from material extraction, manufacturing of construction products, construction and renovation of buildings are estimated at 5...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:improved attractiveness of places through a systemic transition to “Bioeconomy Places”[1], leading to increased investment in the bio-based sectors, job creation and overall well-being of the population, while reducing environmental and climate impacts and promoting sustainable development;sustainable and qualified Bioeconomy Places based on environmental, social and economic indicators, including awareness and skills development, capacity building, food systems sustainability, and contribution to climate action and biodiversity goals, are developed, allowing for comparison (in terms of the elements outlined in this paragraph) and knowledge-sharing between different bioeconomy places. Scope:The local character of biomass and other biological resources and the high number of micro-compani...

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:land managers, farmers, conservation organizations, researchers, policymakers, and agribusinesses are equipped with the knowledge and tools to implement practices that enhance habitats for farmland birds and mammals, thereby improving pest control, supporting pollination, and strengthening agricultural resilience;challenges, measures, and needs of land managers, farmers and conservation organizations are known and supported via appropriate incentives to facilitate the wide adoption of bird- and mammal-friendly practices. Scope:Maintaining and improving farmland bird populations is crucial for both conservation and the long-term sustainability of food production systems. Farmland birds and mammals provide valuable ecosystem services, such as pest control, pollination, and seed dispersal,...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:professionals, consumers and educators adopt innovative repair and refurbishment practices in specific product value chains (electronics, furniture, textiles and footwear), enabling significant reductions in waste, environmental impacts and biodiversity loss, while driving cost savings and job creation in the repair and refurbishment sector;professionals, consumers, local partners, social economy actors and educators have access to high-quality training programs that provide them with technical, business and social skills to repair and refurbish products, thus promoting sustainable consumption and production patterns, climate change adaptation and mitigation, reduction of waste and emissions and enhancing resilience of product value chains. Scope:As the EU strives to reduce waste and pro...