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The goal of this notice of funding opportunity (NOFO) is to support feasibility trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) for conditions that have been identified by NCCIH as high-priority research topics. This funding opportunity is intended to support feasibility clinical trials that provide new information that are scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent competitive full-scale clinical trial. Under this R34, the data collected should be used to fill gaps in scientific knowledge necessary to develop a competitive full-scale clinical trial, including, but not limited to the following: examining feasibility and acceptability of interventions lacking published data; tailoring or adapting the content or structure of an intervention to a specific population, modality, or setting; refining the intervention to determine the most appropriate frequency or duration; determining feasibility of recruitment, retention, and data collection procedures; refining and assessing the feasibility of protocolized multi-component interventions; or examining acceptability and adherence of control conditions. The subsequent...

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO.

This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R01) research is scientifically necessary to design or plan the subsequent fully powered, full-scale clinical trial. Under this R01, the data collected should be used to fill gaps in scientific knowledge, including, but not limited to the following: assessing whether the intervention can be delivered with fidelity across sites; demonstrating feasibility of recruitment, accrual, and randomization of participants across sites; demonstrating participant adherence to the intervention, as well as retention of participants throughout the study across sites; refining and assessing the feasibility of protocolized multimodal interventions, and/or demonstrating feasibility of data collection across sites in preparation for a future fully powered, multisite efficacy or effectiveness trial. The need for multisite fe...

This Notice of Funding Opportunity (NOFO) focuses on prevention and intervention strategies for fetal alcohol spectrum disorders (FASD) throughout the lifespan. The intent of this NOFO is to support research that advances (1) prevention approaches to reduce prenatal alcohol exposure and the incidence of FASD and that (2) interventions for FASD. These objectives will be accomplished with the Exploratory/Developmental Phased Award (R61/R33) mechanism, clinical trial optional. The R61 phase will support pilot studies or secondary data analysis for hypothesis development and feasibility, and research testing the hypotheses can be expanded in the R33 phase. The transition to the R33 phase will be determined by NIAAA program staff after evaluation of the achievement of specific milestones set for the R61 phase. Highest priority will be given to applications with clinical trials. Applicants interested in planning clinical trials or adding to current projects may also consider NOFO (TEMP-23832, the R34 option).

The purpose of this NOFO is to invite Research Project (R01) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Approaches may include but are not limited to empirical qualitative and quantitative methods, as well as conceptual, legal, and normative analyses. Direct involvement of key stakeholders where appropriate is encouraged. This Notice of Funding Opportunity (NOFO) requires a Plan for Enhancing Diverse Perspectives (PEDP) as part of the application. Applications without a PEDP will not be reviewed.

The purpose of this NOFO is to invite Exploratory/Developmental Research Grant (R21) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Approaches may include but are not limited to empirical qualitative and quantitative methods, as well as conceptual, legal, and normative analyses. Direct involvement of key stakeholders where appropriate is encouraged. Of particular interest are studies that explore the implications of new or emerging genomic technologies or novel uses of genomic information. 

Summary: The fiscal year 2026 (FY26) Toxic Exposures Research Program (TERP) Clinical Trial Award (CTA) mechanism supports the advancement, execution, and analysis of clinical trials with the potential to have a significant impact on the prevention, treatment, or management of symptoms, diseases or conditions associated with or resulting from military-related toxic exposures. Proposed projects may range from small proof-of-concept clinical trials (e.g., pilot, first-in-human, phase 0) designed to demonstrate the feasibility or inform the design of more advanced trials, through large-scale trials (including pragmatic clinical trials) to determine efficacy in relevant patient populations.  Distinctive Features: To encourage applications that include meaningful and productive collaborations, the FY26 TERP CTA includes a Partnering Principal Investigator Option (PPIO). One Principal Investigator (PI) is identified as the initiating PI, and an additional PI may be identified as a Partnering PI. If recommended for funding, each PI will be named on separate awards. The intent is to support interdisciplinary partnerships, such as those between clinicians and research scientists, that will accelerate the movement of promising interventions/​knowledge products into clinical applications. Partnering should significantly advance the research beyond what would be possible through independent efforts. https://cdmrp.health.mil/pubs/press/2026/terppreann

Summary: The intent of the fiscal year 2026 (FY26) Toxic Exposures Research Program (TERP) Translational Research Award (TRA) is to support translational research that will accelerate the movement of promising ideas in military-related toxic exposure research into clinical applications, including health care products, interventions, technologies and/or clinical practice guidelines. Translational research may be defined as an integration of basic science and clinical observations. New Approach Methodologies may also be used. Applications should provide evidence for the reciprocal transfer of information between basic and clinical science, or vice versa, in developing and implementing the research plan.  Distinctive Features: To encourage applications that include meaningful and productive collaborations, the FY26 TERP TRA includes a Partnering Principal Investigator Option (PPIO). One Principal Investigator (PI) is identified as the initiating PI, and an additional PI may be identified as a Partnering PI. If recommended for funding, each PI will be named on separate awards. The intent is to support interdisciplinary partnerships, such as those between clinicians and research scientists, that will accelerate the movement of promising ideas into clinical applications. Partnering should significantly advance the research beyond what would be possible through individual efforts. https://cdmrp.health.mil/pubs/press/2026/terppreann

Summary: The fiscal year 2026 Toxic Exposures Research Program (TERP) Investigator-Initiated Research Award (IIRA) is intended to support studies that will make an important contribution toward research and/or patient care for diseases or conditions associated with military-related toxic exposures. Research projects may focus on any phase of research from basic laboratory research through translational research, including preclinical studies in animal models and human subjects, as well as correlative studies associated with an existing clinical trial. New Approach Methodologies may also be used. https://cdmrp.health.mil/pubs/press/2026/terppreann

The Louis Stokes Alliances for Minority Participation (LSAMP) program invests in the Nation's colleges and universities to aid student success to create a new generation of STEM discoverers for the national STEM enterprise. The program takes a comprehensive approach to the STEM Learning Ecosystem to impact STEM student development and retention. LSAMP is an alliance-based program, whereby a group of institutions of higher education (IHEs) work together to diversify the nation's science, technology, engineering, and mathematics (STEM) workforce by increasing the number of STEM baccalaureate and graduate degrees awarded to persons from LSAMP populations. LSAMP populations are defined as persons from groups underrepresented in the STEM enterprise: Blacks and African-Americans, Hispanic and Latino Americans, American Indians, Alaska Natives, Native Hawaiians, and Pacific Islanders. The LSAMP program provides funding to alliances that implement comprehensive, evidence-based, innovative, and sustained strategies that ultimately result in the graduation of well-prepared, highly competitive students from LSAMP populations who pursue graduate studies or careers in STEM, while also supporting knowledge generation, knowledge utilization, assessment of program impacts, dissemination activities and dissemination of scholarly research into the field. Projects supported by the LSAMP program include: --Alliance Development Grants (ADG) support the conceptualization and development of new B2B and new SPIO alliances. (New) --Bridge-to-the-Baccalaureate (B2B) alliances facilitate the successf...

The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.

The National Institutes of Health (NIH) hereby notifies NIH award recipients that funds may be available for revision applications to support the expansion of existing projects and/or programs within the awarding IC identified in the competitive revision Notice of Special Interest (NOSI). Applications for Revisions will be evaluated for scientific and technical merit by (an) appropriate Scientific Review Group(s), in accordance with NIH peer review policy and procedures, using the stated review criteria. Only applications submitted in response to a NOSI published by an NIH Institute or Center will be allowed to apply to this NOFO.

Expected Outcome:Project results are expected to contribute to the following outcomes:For supported doctoral candidatesNew research and transferable skills and competences, leading to improved employability and career prospects within and outside academia;New knowledge allowing the conversion of ideas into products and services, where relevant;Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact. For participating organisationsImproved quality, relevance and sustainability of doctoral training programmes and supervision arrangements;Enhanced cooperation and transfer of knowledge between sectors and disciplines;Increased integration of training and research activities between participating organisations;Boosted R&I capacity;Increased internationalisation and attractivene...

Expected Outcome:This action builds on the MSCA Doctoral Networks 2026 call (HORIZON-MSCA-DN-2026).The project results are expected to contribute to the following outcomes:For supported doctoral candidates:New research and transferable skills and competences in the application of AI in science, leading to improved employability and career prospects within and outside academia;New knowledge allowing the conversion of ideas into products and services, where relevant;Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact. For participating organisations:Improved quality, relevance and sustainability of doctoral training programmes and supervision arrangements;Enhanced cooperation and transfer of knowledge between sectors and disciplines;Increased integration of training and...

Expected Outcome:The EIC STEP Scale Up call offers a total indicative budget of EUR 300 million for 2026, which is expected to rise to EUR 900 million for the period 2025-2027. Any unused amount from this budget will be allocated with priority to the EIC Accelerator Open call.The support will be in the form of equity-only investments managed by the EIC Fund. Applicants to this call will not receive a grant component. It provides significant financial support, and applicants should apply for an investment of a minimum of EUR 10 million and maximum of EUR 30 million, to co-invest in a funding round in the range of EUR 50 to 150 million, and at least three to five times the amount of the requested EIC contribution. The specific terms of each investment are considered and negotiated on a case-by-case basis in accordance with the EIC Fund Investment Guidelines. This ensures the investment is...

Expected Outcome:The successful proposal is expected to further contribute to the expected outcomes specified in topic HORIZON-CL6-2024-GOVERNANCE-02-01: European Partnership of Agriculture of Data, for continuation of the activities in line with already agreed outcomes. Scope:The objective of this action is to continue to provide support to the European partnership of Agriculture of Data identified in the Horizon Europe Strategic Plan 2021-2024 and first implemented under the topic HORIZON-CL6-2024-GOVERNANCE-02-01: European Partnership of Agriculture of Data, and in particular to fund additional activities (which may also be undertaken by additional partners) in view of its intended scope and duration, and in accordance with Article 24(2) of the Horizon Europe Regulation.The consortium which applied to and received funding under HORIZON-CL6-2024-GOVERNANCE-02-01: European Partnership o...

Supports mathematical research in areas where computation plays a central and essential role, emphasizing analysis, development, and implementation of theoretically justified and efficient algorithms. The combination of these elements resulting in innovative computational methods is a hallmark of the program. Proposals ranging from single investigator to interdisciplinary team projects that not only create and analyze new computational mathematics techniques but also implement them to model, study, and solve important application problems are strongly encouraged, as is providing opportunities for rigorous mathematical training of junior computational mathematicians through research involvement. Conferences Proposals to the Computational Mathematics Program for conferences or workshops must be submitted through the program solicitation "Conferences and Workshops in the Mathematical Sciences" (link below). Principal Investigators should carefully read the solicitation to obtain important information regarding the substance of proposals for conferences, workshops, and similar activities. Unless an exception from the program is granted, to facilitate timely notification of the availability of support, the following requirements are in effect: Proposals for conferences, workshops, etc., to be held in the US must be submitted at least 6 months in advance of the conference start date; Proposals to support group travel to meetings outside the US must be submitted at least 8 months in advance of the meeting start date; Proposals for conferences, workshops, etc., whose budget request...

The Archaeology Program administers an annual Archaeometry competition with a target date of December 1. The goal is to fund projects in two main categories: To develop or refine anthropologically relevant archaeometric techniques. Examples include the development of methods to identify specific types of organic residues on ceramics or development of field applicable analytic techniques. To support laboratories which provide relevant services. This includes support of service laboratories which, for example, may provide dating trace element, isotopic and dendrochronological analyses. It also includes support for data archives, which function to strengthen basic archaeological infrastructure. Projects which apply standard archaeometic techniques with the goal to answer specific archaeological questions should be submitted to the Archaeology SeniorResearch Awards competition. Proposals are evaluated by both ad hoc reviewers and a panel composed of individuals who combine both archaeological and archaeometric expertise.

Expected Outcome:Deep sedimentary/basement reservoirs are usually characterized by low permeability, high drilling cost and a scarcity of data, as they are typically ignored by hydrocarbon exploration. Major exploration challenges relate to predicting deep sedimentary and basement reservoir structures and properties to identify suitable locations for reservoir-independent approaches, capable of overcoming the low permeability obstacle, such as Enhanced Geothermal Systems (EGS) or closed-loop geothermal systems.Project results are expected to contribute to all of the following expected outcomes:Increased knowledge base for developers to unlock unexploited geothermal resources, increase drilling success rate, increase geothermal sources performance and reduce the risk of induced seismicity and deploy geothermal energy in a sustainable way in environmental (notably on biodiversity and pollu...

Expected Outcome:Agrivoltaics or the co-location of agricultural activity and PV electricity production is a novel form of PV deployment which could provide farmers with diversified revenue sources and ecological benefits, while reducing land use competition, siting restrictions or adverse impacts on biodiversity and agricultural production. Optimizing system designs and business practices will help to enable simultaneous land use creating synergy for both agriculture and electricity production; this can benefit farmers, lower PV costs and enable the European Union to reach the goals of the EU solar energy strategy.Similarly, offshore/nearshore PV systems represent a tremendous deployment potential in Europe and globally, due to their advantages in conserving land resources and optimizing light utilization. However, prevailing technical challenges limit deployment in most sea conditions...

Expected Outcome:Fully sustainable regional bioenergy value chains and efficient conversion can play an important role in renewable efficient power and heating generation and for reaching the EU climate and energy targets and contribute to European competitiveness and energy security.Project results are expected to contribute to at all of the following expected outcomes:The demonstration of regional value chains for the use of locally to regionally sourced sustainable and cheap solid biofuel from upgraded biogenic residues and wastes in line with the provisions of the Renewable Energy Directive in high efficiency CHP plant creates opportunities for SMs, regional value generation and European knowledge advancement and international competitiveness in the sector. Provide flexible renewable power and heat to local industries for their processes and allow for high penetration of renewables i...

Expected Outcome:Projects are expected to contribute to all the following expected outcomes:Effective and innovative methods for gathering, sharing and using large data sets in energy applications for the purpose of training AI models while ensuring privacy and security.Advanced and - wherever possible - open-source AI foundation models to support the digitalisation of the energy system, through improved grid observability, forecasting of supply and demand, advanced storage and renewables integration, demand side flexibility and energy efficiency.Enhanced cooperation, knowledge sharing and interoperability among energy system actors for secure and seamless data exchange.Advanced methodologies for AI model development ensuring that the results are FAIR (Findable, Accessible, Interoperable, Reusable) beyond the project ending, open source and accommodating for technology evolution. Scope:T...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Robust evidence on how inhabitants experience their neighbourhood[1] and the impact of these experiences on their health and well-being.The research informs policies, strategies, neighbourhood planning and procurement for the green transition[1] of neighbourhoods, including their nature-positive[3] transformation and climate resilience. Scope:Neighbourhoods are human-social constructs and environments. They are shaped by complex inter-connections and interdependencies of human and non-human actors in the natural and built environment[1] they comprise. An increasing body of research is looking at the relationship between people and the built environment, from neuro-architectural aspects of space to atmosphere and ambiance aspects in urban design and planning, influencing also the percepti...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Evidence of the structural social infrastructure[1] and services needed to address homelessness[1] at neighbourhood[1] level is made available to stakeholders involved in tackling homelessness.Improved availability and accessibility of key social infrastructure and services for homeless groups in the targeted neighbourhoods. Scope:Based on 2024 data, over 1.2 million people are estimated to experience homelessness in Europe[4], with a significant proportion (45%) of surveyed homeless individuals finding themselves in a situation of chronic homelessness for over two years[5].While housing-led approaches[1] are crucial to tackle homelessness, addressing the structural and multidimensional causes of homelessness also requires systemic interventions focusing on social infrastructure and serv...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:An increased number of local authorities systematically identify and quantify vacant, obsolete or underutilised spaces for reuse in neighbourhoods[1] in a context-sensitive way to address local community[1] challenges and needs.Increase in renovated, renatured, or converted spaces that address local community challenges and needs. Scope:Europe’s housing needs, inefficient use of the existing building stock, environmental commitments, and the EU’s goal of “no net land take” by 2050 make a compelling case for reusing the significant number of existing spaces, including buildings and infrastructure, that are vacant, obsolete or underutilised. In Europe, there are, for instance, an estimated 19,000 km² of underutilised brownfield land and 300 km² of vacant or underutilised office space[3].Th...