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Expected Outcome:The successful proposal will contribute to the implementation of the EU Mission on Adaptation to Climate Change and the upcoming European Climate Adaptation Plan. Proposals are expected to contribute to all of the following outcomes:The wide range of solutions tested and deployed in the context of the Adaptation Mission and the good practices emerged in its Community of Practice are harvested, assessed, structured and systematised to support the implementation of the Mission.Regional and local authorities can access, in the local language, the latest and most actionable solutions for climate adaptation relevant to their (climatic) conditions. Adaptation solutions stemming from research and innovation are ready for replication and scale-up, contributing to the delivery of the Adaptation Mission and acceleration of adaptation efforts across Europe. Legacy of the knowledge...

Expected Outcome:Successful proposals will support the implementation of the EU Adaptation Strategy, the EU Mission on Adaptation to Climate Change, the European Water Resilience Strategy, the EU Preparedness Strategy and the upcoming European Climate Adaptation Plan. Proposals are expected to contribute to all of the following outcomes:Navigable inland waterways, their surroundings and related infrastructure are managed in a more integrated and sustainable manner across Europe and become more climate-resilientClimate and environmental risks to water infrastructure (e.g. droughts, flooding, slow onset events, ecological degradation and cascading and compound events) are more effectively addressed in a systemic way. Safe, efficient and reliable navigability conditions are improved.Cost-efficient and environmentally friendly measures -- especially nature-based solutions -- are identified w...

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Care Award (TrCA) supports clinical research or clinical trials evaluating interventions, innovations, and solutions in critical areas for dementia care for individuals with Alzheimer’s disease and Alzheimer’s disease related dementia (AD/ADRD) and their care partner(s).Distinctive Features:Clinical research and clinical trials are allowed; however, clinical trials solely testing or evaluating pharmacological interventions do not meet the intent of this funding opportunity.Studies utilizing animal models do not meet the intent of the mechanism and are not allowed.Preliminary data are required.Community collaboration is required for research prospectively enrolling human subjects.The AZRP encourages studies to leverage existing cohorts/datasets. Cohorts consisting of individuals 65 years or younger are also encouraged.Career Initiation or Transition (CIT) Partnership Option: The TrCA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet the CIT Partnership Option eligibility requirements at the time of application submission.

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Diagnosis Award (TrDA) supports non-incremental, solutions-oriented research that reduces or overcomes important barriers to obtaining a diagnosis, meaningful disease monitoring and accurate prognosis.Distinctive Features:Clinical research is allowed, however clinical trials and animal research are prohibited. Preliminary data are required.Community collaboration is required for studies prospectively enrolling human subjects.Study Population: The AZRP encourages studies to leverage existing cohorts/datasets. Cohorts consisting of individuals 65 years or younger are also encouraged.Career Initiation or Transition (CIT) Partnership Option: The TrDA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet the CIT Partnership Option eligibility requirements at the time of application submission.

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Research Award (TrRA) supports non-incremental, robust, well-designed research that drives transformative advancements in reducing risk and preventing the development of Alzheimer’s disease and/or Alzheimer's disease related dementias (AD/ADRD).Distinctive Features:• Applications must address at least one of the following focus areas: ○ Risk Factor Knowledge: Research that advances understanding, identification, and/or validation of risk and/or protective factors, with research outcomes/products focused on accelerating solutions. Projects may include, but are not limited to, research on environmental, epigenetic, genetic, lifestyle, occupational, or other risks not listed here. ○ Risk Reduction Solutions: Research that describes methods, technologies, and strategies that contribute to reducing risk and preventing AD/ADRD.• Clinical research is allowed, however clinical trials and animal research are prohibited.• Preliminary data are required.• Community collaboration is required for research prospectively enrolling human subjects.• Career Initiation or Transition (CIT) Partnership Option: The TrRA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet

Expected Impact:In the short term, the funding is expected to:Increase understanding and dissemination of challenges, risks and good practices in the priority areas identified under this call;Enhance communication, coordination and operational cooperation between authorities responsible for the prevention, detection and repression of corruption;Improve the availability and use of data, methodologies and tools for measuring corruption risks, trends and the impact of anti-corruption measures. Where applicable, proposals should demonstrate how they build on relevant previous or ongoing EU-funded projects and existing corruption measurement frameworks.In the long term, the funding is expected to:Improve the prevention, detection, investigation and prosecution of corruption across the EU;Contribute to the implementation of EU anti-corruption policy priorities, including recommendations addres...

Expected Outcome:The Synergy action for Teaming Centres of Excellence (CoE) responds to the need to ensure the sustainability of CoE funded under the Teaming calls[1]. The establishment of CoE in Widening countries, supported by a significant investment in Horizon 2020 and Horizon Europe, has created new opportunities for scientific, societal, and economic impact. However, to fully capitalise on this investment and enhance the sustainability and international competitiveness of these CoE, it is essential to facilitate stronger collaboration and strategic joint initiatives among them.Proposals are expected to contribute to all the following outcomes:Stronger long-term collaboration among Teaming CoE through structured joint initiatives and clustering efforts to enhance mutual learning, resource sharing, and collective research and innovation capacity;Strategic transformation of R&I system...

Expected Outcome:Excellent capacities in research management are essential for institutions and national R&I systems to enhance their research excellence and capitalize on their R&I activities in a knowledge-based economy and society. The Research Management Facility aims at providing institutions in Widening countries that want to establish or upgrade their research management capacities with tailored support. The Research Management Facility also advises on an implementation strategy to introduce changes in the institutional set-up, in line with the ERA priorities. However, the action does not provide support for the implementation of the strategy.Strong research management ensures effective grant acquisition, resource allocation, compliance with funding regulations, and strategic planning. It supports high-quality research by streamlining administrative processes, facilitating interdi...

Expected Outcome:The Hop-on Facility allows for legal entities from Widening countries to join already funded Horizon Pillar II ‘main’ work programme and EIC Pathfinder collaborative R&I actions, subject to the agreement of the respective consortium and provided that legal entities from such countries are not yet participating as beneficiary, associated partner, or affiliated entity. The scheme aims to improve the inclusiveness of Horizon Europe. Selected consortia will be invited to submit a grant agreement amendment request of the eligible already funded action.Project results are expected to contribute to the following outcomes:At system level, mobilise excellence in the Widening countries, increase visibility of the beneficiaries from the widening countries, improve knowledge circulation, and boost their participation in specific thematic domains;At consortium level, open up establis...

This funding opportunity announcement (FOA) encourages grant applications that support the activities of the National Primate Research Centers (NPRCs). Nonhuman primates (NHPs) are most closely related to humans, both physiologically and genetically. Therefore, NHPs are critical animal models for basic and translational research aimed at understanding human biology, both in normal and diseased states. Proper husbandry and management of NHPs require specialized physical and intellectual resources, which are most effectively and economically provided in centralized primate centers, the resources of which are made available to investigators on a national basis. The NPRCs provide these resources to investigators/grantees who utilize NHPs in biomedical research and thereby complement and help enable the missions of the NIH Institutes and Centers.

Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPORE). The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. For the purpose of this FOA, a group of highly related cancers are those that are derived from the same organ system, such as gastrointestinal, neuroendocrine, head and neck, and other cancers. Other programmatically appropriate groups of cancers may include those centered around a common biological mechanism critical for promoting tumorigenesis and/or cancer progression in organ sites that belong to different organ systems. For example, a SPORE may focus on cancers caused by the same infectious agent or cancers promoted and sustained by dysregulation of a common signaling pathway. In addition, a SPORE may focus on cross-cutting themes such as pediatric cancers or cancer health disparities. The research supported through this program must be translational and must stem from research on human biology using cellular, molecular, structural, biochemical, and/or genetic experimental approaches. SPORE projects must have the goal of reaching a translational human endpoint within the project period of the grant.

The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The projects may be supported by core units, if justified, to facilitate economy of effort, space, and equipment. The NHLBI provides support for Program Project Grants (PPGs) in the belief that collaborative research efforts can accelerate the acquisition of knowledge more effectively than a simple aggregate of research projects that have no interaction or thematic integration. NHLBI is particularly interested in encouraging new scientific directions in PPGs. Use of the P01 activity code is viewed as an opportunity to attract scientists who have not traditionally been supported by the NHLBI. Further, the PPG environment presents an opportunity for emerging scientific leaders to gain insight into how to lead a successful scientific Program, and applicants will have the opportunity to include a project led by an Early Stage Investigator (ESI). All projects in the Program must be interrelated and have objectives that address a central theme within the scientific mandate of the NHLBI.

The goal of the NIGMS Predoctoral Basic Biomedical Sciences Research Training Program is to develop a pool of well-trained scientists available to address the Nations biomedical research agenda. Specifically, this funding opportunity announcement provides support to eligible, domestic institutions to develop and implement effective, evidence-informed approaches to biomedical graduate training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation.

The purpose of the Resource-Related Research Projects (R24) grant is to support investigator-initiated resources designed to provide materials and services to support and advance biomedical research on a national basis. An R24 resource grant mechanism is a non-hypothesis-driven activity to provide data, materials, tools, or services that are essential to making timely, high quality, and cost-efficient progress in a field. Hypothesis-driven research applications should not be submitted in response to this program announcement but to another mechanism that encourages this type of research. The resource should be available to any qualified investigator, and should be highly quality controlled, and not duplicate resources available commercially or through other sources. Resources should be designed to provide services to the broad alcohol research community and should not be limited by any specific regional focus.

The Office of Research Infrastructure Programs (ORIP) invites grant applications from core facilities, resource centers, animal vivaria, or individual investigators of other shared resources to systematically study the roles of critical environmental extrinsic factors in biological, behavioral, and treatment studies using animal model species, with the objective of enhancing the rigor and reproducibility of animal research. The research area must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate the biological processes that impact multiple organ systems in order to align with the ORIPs NIH-wide mission and programs. The program supports the acquisition or update of modern equipment for measuring, monitoring, recording, and reporting environmental, biological or biobehavioral variables. The equipment requested must be capable of recording and reporting multiple parameters simultaneously.

This Notice of Funding Opportunity (NOFO) invites eligible academic or research institutions to apply for funding support to purchase latest scientific equipment that will enhance and modernize research-supporting operations of existing shared biomedical research facilities. Targeted are laboratory research core facilities, animal research facilities, and other similar shared-use research spaces. The goal of this NOFO is to strengthen research-auxiliary activities of biomedical research facilities and to enhance the efficiency of their operations. The NOFO does not support the purchase of scientific research instruments or their components, nor components of building-level infrastructure equipment that indirectly support research activities.

The specific purpose of this Notice of Funding Opportunity (NOFO) is to promote the development of a diverse, interdisciplinary workforce needed to conduct translational research on Alzheimer's disease and Alzheimer's-related dementias from target discovery through clinical development. This NOFO will support institutional training programs for predoctoral and postdoctoral level researchers with diverse educational backgrounds (i.e., basic biology, translational and clinical research, data science). The program invites eligible institutions to develop interdisciplinary training programs that will provide trainees with the knowledge and skills in data science, disease biology, behavioral research, and traditional and emerging drug discovery disciplines necessary to conduct rigorous and cutting-edge basic, translational, and clinical research for AD/ADRD.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to encourage individuals who have not had substantial biomedical research experience, or who have the potential to significantly benefit from additional biomedical research experience to pursue further studies or careers in research. To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on: (1) Research Experiences, (2) Curriculum or Methods Development and (3) Outreach. The NCI’s mission is to conduct and support research, training, health information dissemination, and other programs concerning cancer. This funding opportunity seeks to facilitate educational activities that encourage students to become knowledgeable about cancer and available to focus on cancer later in their careers. To promote broad interest in pursuing a career in biomedical research via early intervention strategies, the NCI Youth Enjoy Science (YES) Program will support efforts to create and maintain an institutional program to engage grades 6-12 and/or undergraduate students in cutting edge cancer research experiences. The proposed institutional programs may also provide research experiences for the grade 6-12 teachers and undergraduate faculty members. The goals are to inspire interest in biomedical sciences, help envision research as a career path, and strengthen practical research and career skills. In alignment with these goals, institutions may develop unique programs that capitalize....

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded UM1 Clinical and Translational Science Awards (CTSA) Program Hubs (PAR-24-272). Successful programs supported through this funding opportunity are expected to lay a strong foundation for future adoption and/or dissemination of capabilities to additional CTSA Program Hubs.

Our world is at a pivotal moment where the boundaries dividing the physical and social worlds from the cyber world have become blurred. Cyberspace has evolved from an interconnected digital environment into a complex and interdependent cyber ecosystem that involves hardware, software, networks, data, people, organizations, countries, and the physical world. Critical functions of everyday life are deeply intertwined with computing, including health, government, commerce, the public sphere, education, critical infrastructure, interpersonal communication, and transportation. The complexity and inter-dependencies in cyberspace can be misused and exploited by malicious actors. These in turn can trigger adverse outcomes such as disruption of critical infrastructure and systems; theft of intellectual property and sensitive data; amplification of inequalities; disclosure of private information of individuals, organizations, and governments; and threats to lives, livelihoods, and reputations. Furthermore, constant attacks on the data and assets of corporations, governments, and individuals undermine people’s trust in decision-making and processes that depend critically on these cyber systems. The Security, Privacy, and Trust in Cyberspace (SaTC 2.0) program aims to build trust in global cyber ecosystems. Trust is the core tenet of this program and, for the purposes of this solicitation, is broadly defined to include our confidence in the security, privacy, and resilience of cyberspace, particularly in the face of malicious intent. Achieving this level of confidence in cyberspace req...

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NIDCD R25 program is to support educational activities that help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences.

The integration of Artificial Intelligence (AI) and Biological Research has the potential to pave the way for breakthroughs in biotechnology and bio-system design that will create innovations, new industries, and jobs. To capitalize on this promise, the Directorate for Biological Sciences (BIO) will make awards for Postdoctoral Research Fellowships in Biology (PRFB) to recent doctoral degree recipients, for proposals with a research and training focus at the Intersection of Artificial Intelligence and Biological Sciences to Strengthen and Safeguard Biotechnology Innovations. Applying AI to highly complex biological systems will reveal unknown mechanisms in the natural world that hold promise for technological developments. Candidates with AI and/or biology experience will develop deep expertise in both by proposing additional training in both areas. These combinations of current expertise and new cross-training will produce scientists who work seamlessly at the intersection of AI and biology. The fellows are expected to become field leaders who use AI capabilities to extrapolate from biological data to technological advances. Proposers are encouraged to consider how to leverage the nation’s diversity of existing biological data, and biological infrastructure, such as Biofoundries, Programmable Cloud Labs, Manufacturing USA Institutes, and NEON, to accelerate discovery, innovation and the biotechnology that improves human lives, promotes the U.S. economy, and benefits the nation.

Scope:Smart and multifunctional textiles allow various components and devices to be integrated into uniforms and soldier systems. This extends their range of functions, which can include environmental and physiological monitoring of the soldier, localisation, communication, protective functions (e.g. concealing a soldier's visual, radar and electromagnetic signatures from enemy sensors and surveillance technologies, fire protection and neutralisation of hazardous chemicals). Russia’s war of aggression against Ukraine has highlighted the critical operational need for protection of dismounted soldiers, particularly against drones, and triggered the definition of updated soldier system requirements.The objective of this topic is to follow up and complement previous activities in the field of smart and multifunctional textiles with a view to developing an individual camouflage solution, both...

Scope:Due to the changing overall geopolitical context, Member States, EDF associated countries and their land forces need to improve their indirect fire and rocket artillery capabilities in particular, as many have been relying on non-European systems that are already approaching the end of their operational life.Against this background, this topic aims to develop multiple rocket launcher solutions capable of countering the latest threats by increasing the range and precision of indirect fire, maximising interoperability and optimising the cost-effectiveness of operations in a high-intensity and GNSS-contested battle scenario.This topic contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of defence technologies. Targeted types of activities: Studies and design, not excluding upstream and downstream activities eligible for development action...

Scope:The increasing complexity of military operations requires more advanced electronic warfare (EW) systems capable of dealing with multiple threats and operating in electromagnetic congested scenarios. Current solutions are partially effective and require the complex integration of different sensors and frequency bands. As a result, there is a growing need for automated EW systems that can rapidly identify and respond to threats, especially given the limited availability of qualified personnel.To meet this challenge, this topic aims to further develop and integrate technologies to develop a more robust, cognitive and operational EW system. Cognitive EW systems that use AI and machine learning can detect, learn and interact with the environment, accelerating the development and implementation of next-generation EW threat detection, suppression and neutralisation technologies. These sys...