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The Employment and Training Administration at the U.S. Department of Labor (DOL) is soliciting applications in support of the administration of the Supporting Effective Educator Development (SEED) program on behalf of the U.S. Department of Education (ED). The SEED program provides funding to increase the number of highly effective educators by supporting the implementation of evidence-based practices that prepare, develop, or enhance the skills of educators to improve student outcomes. These grants will allow eligible entities to develop, expand, and evaluate practices that can serve as models to be sustained and disseminated.Applicants can receive competitive preference points to projects or proposals endorsed by a Governor or chief State education official for purposes of implementing the project or proposal. Applicants can also receive competitive preference points for projects or proposals that are designed to responsibly advance artificial intelligence and/or prioritize and expand Registered Apprenticeships.

The Housing Policy Research Grant Notice of Funding Opportunity provides competitive awards to eligible applicants, including institutions of higher education, nonprofit, and for-profit institutions. Awards made through this NOFO will fund quality research projects that: (1) contribute to knowledge about housing policy in the United States; and (2) generate actionable insights and evidence that can applied by policymakers and communities in the short-term.

This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical model to demonstrate that a proposed therapeutic agent warrants further development. In addition to preclinical efficacy, accompanying pharmacodynamic and pharmacokinetic studies would be supported. Therapeutic agents include small molecules, biologics or biotechnology-derived products. The goal of this NOFO is to spur therapeutic development for a variety of rare diseases by advancing projects to the point where they would attract subsequent investment supporting full Investigational New Drug (IND) application development or progression to clinical trials in the case of repurposing or repositioning.

This NOFO supports basic or applied research and development of Innovations in forensic science for criminal justice purposes. These awards support a discrete, specified, circumscribed project that will: 1. Increase the body of knowledge to guide and inform forensic science policy and practice; or 2. Lead to the production of useful material(s), device(s), system(s), or method(s) that have the potential for forensic application.

This NOFO seeks proposals for rigorous applied research and evaluative studies on the forensic science system. The field of forensic science is changing, particularly as technological advancements improve the criminal justice system’s ability to use forensic evidence more effectively and efficiently. Research is needed to better understand the impact of forensic science on the criminal justice system and law enforcement operations. With this NOFO, NIJ requests applications in three topic areas: • The impact of forensic science on the criminal justice system and law enforcement operations, such as improving investigative clearance rates, increasing law enforcement effectiveness, and reducing crime lab backlogs. • Evaluations of the implementation of new and innovative forensic science methods and their impact on strengthening courtroom admissibility and evidentiary reliability. • Developing the forensic science workforce.

This funding opportunity seeks rigorous proposals on: (1) management and development of the correctional workforce; and (2) correctional officer safety. Proposals for research outside of these two topics will not be considered responsive to this NOFO. Applicants may submit more than one proposal; however, only one topic may be submitted per proposal. Applicants are requested to identify the topic addressed in their application on the title page of the proposal narrative. NIJ is particularly interested in applications with research designs that incorporate action-oriented research, where jurisdictions are an integral part of defining the program, implementing change, and revising practices based on assessment of the change. Applicants may propose a phased implementation plan if the research design and questions warrant this approach.

This funding opportunity seeks proposals for research and evaluation studies to produce practical knowledge that can improve the examination and interpretation of physical evidence in forensic science laboratories. Specifically, NIJ seeks applications for rigorous research and evaluation projects that will: • Identify and inform the forensic community of best practices through the evaluation of existing and emerging laboratory protocols; and/or • Have a direct and immediate impact on laboratory efficiency and assist in making laboratory policy decisions.

This funding opportunity seeks to fund rigorous and innovative research and evaluation projects to fill knowledge gaps in two topical areas: 1) research on malleable factors that affect school violence in K-12 schools; and 2) evaluations of the impact and effectiveness of school safety approaches implemented for purposes authorized under the STOP School Violence Act. This NOFO is released by the National Institute of Justice (NIJ) in partnership with the Bureau of Justice Assistance (BJA).

The purpose of this notice of funding opportunity (NOFO) is to support the establishment or continuation of longitudinal infant cohorts to determine and compare how initial and repeated natural influenza infections and/or influenza vaccinations shape infant and childhood immunity to future influenza exposures. The goal of this research is to understand how these exposures influence immune responses to subsequent influenza infections and/or vaccines and provide key information to facilitate design of durable, broadly protective influenza vaccines.

The USGS Earthquake Hazards Program (EHP) issues this Notice of Funding Opportunity (NOFO) for assistance to support research in earthquake hazards, the physics of earthquakes, earthquake occurrence, and earthquake safety policy. This activity is authorized by the Earthquake Hazards Reduction Act of 1977 (Public Law 95-124, 42 U.S.C. 7701 et. seq.), and as amended by the National Earthquake Hazards Reduction Program Reauthorization Act of 2018 (Public Law 115-307).It is estimated that a total of $4 million will be awarded in support of competitive research grants in FY2027, with a maximum total of $7 million. Based on awards in recent years, approximately 50 to 70 new awards are funded each fiscal year. There is no maximum award amount (i.e., any amount may be proposed if it can be justified appropriately), however, the majority of grants range between $30,000 and $120,000. This estimate does not bind the USGS to a specified number of awards or to the amount of any award unless that amount is specified by statute or regulation.This U.S. Geological Survey (USGS) competitive grants solicitation supports external research partnerships that are essential to the Earthquake Hazards Program (EHP) mission. The goal is to generate scientific information and situational awareness products that help the program reduce deaths, injuries, and economic losses from earthquakes, and improve public safety and resilience nationwide. External grants with university, state, regional and local government agencies, and private industry partners support science that cannot be conducted within the....

This NOFO is released by the National Institute of Justice (NIJ) in partnership with the Office for Victims of Crime (OVC). The funding opportunity seeks to build upon past research and evaluation efforts by focusing on emerging evidence needs and remaining gaps to combat human trafficking and protect children, with a particular focus on trafficking at the Southern Border. Applicants should propose projects that will have a clear effect on U.S. criminal justice policy and practice. This NOFO calls for applications in two categories: • Category 1: Justice System Responses to Trafficking (Anticipated Award Amount: $3,000,000) This category seeks applications for research and evaluation projects on strategies to improve trafficking investigations, prosecutions, and disruption of human trafficking networks, particularly along the Southern border; and evaluations of well-developed direct service programs to help American child and adult victims of labor and sex trafficking. • Category 2: Technology and Trafficking (Anticipated Award Amount: $1,000,000) This category seeks applications for research and evaluation at the intersection of technology and trafficking, especially relating to technology used by traffickers and technologies used to investigate and build cases.

This NOFO seeks applications for rigorous applied research on the intersection of drug crimes and firearms to inform the development of evidence-based tools, practices, and policies for state, tribal, and local law enforcement and other criminal justice stakeholders that address drug trafficking, drug markets, and drug-related violence. With this FY25 NOFO, NIJ seeks applications in four topic areas: (1) Pattern Identification; (2) Interdiction & Disruption Strategies; (3) Prosecution; and (4) Drug Market Dynamics.

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage institutions to propose creative and innovative institutional research career development programs which will prepare clinically trained vision scientists for independent research careers. This NOFO is intended to expand and strengthen the community of clinician investigators engaged in vision research. This Notice of Funding Opportunity (NOFO) allows the appointment of Scholars proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator as part of their research and career development program. For this career development program scholars are limited to clinical trials that are minimal risk. The existing clinical trial must be a NIH-defined clinical trial that fulfills the NIH requirement for minimal risk trial. A minimal risk trial is one in which the probability and magnitude of harm or discomfort anticipated in the research are not greater in and of themselves than those ordinarily encountered in daily life or during the performance of routine physical or psychological examinations or tests. Applicants are strongly advised to consult with NEI program staff prior to submitting an application with human subjects to determine the appropriate funding opportunity.

The Office of Nuclear Energy (NE) mission is to advance nuclear energy science and technology to meet U.S. energy, environmental, and economic needs. NE has identified the following goals to address challenges in the nuclear energy sector, help realize the potential of advanced technology, and leverage the unique role of the government in spurring innovation: · Enable continued operation of existing U.S. nuclear reactors · Enable deployment of advanced nuclear reactors · Develop advanced nuclear fuel cycles · Maintain U.S. leadership in nuclear energy technology NE strives to promote integrated and collaborative research conducted by national laboratory, university, industry, and international partners under the direction of NE’s programs, and to deploy innovative nuclear energy technologies to the market and to optimize the benefits of nuclear energy.

The Employment and Training Administration at the U.S. Department of Labor (Labor) is soliciting applications in support of the administration of the Teacher and School Leader Incentive Program (TSL) program on behalf of the U.S. Department of Education (ED). The purpose of the TSL program is to assist States, local educational agencies (LEAs), and nonprofit organizations to develop, implement, improve, or expand comprehensive performance-based compensation systems (PBCS) or human capital management systems (HCMS) for teachers, principals, or other school leaders (especially for teachers, principals, or other school leaders in high-need schools) who raise student growth and academic achievement, support workforce readiness, and close the achievement gap between high- and low-performing students. In addition, a portion of TSL funds may be used to study the effectiveness, fairness, quality, consistency, and reliability of PBCS or HCMS for educators.Grant application reviewers will award competitive preference points to projects or proposals that will be carried out by State educational agencies grantees. This priority aligns to the Administration"s efforts to ensure Federal education dollars empower states to best meet their teachers" and students" needs. Applicants can also receive competitive preference points for projects or proposals that are designed to advance meaningful learning, including high-quality and proven interventions that will directly benefit student learning outcomes.

This NOFO seeks rigorous, applied evaluative research on: (1) existing police training; (2) officer safety and health; (3) criminal investigations; and (4) policing strategies and tactics.

The purpose of this NOFO is to support the creation of standards and related efforts that will allow researchers to easily access data from personal tracking devices. The awardees will be expected to partner with device manufacturers as well as the researcher community if the effort is going to be successful. It is expected that the awardees will create standards for personal tracking device data that serve the same purpose as the DICOM or Neuroimaging Informatics Technology Initiative (NIfTI) formats and standards do for medical image files.

This NOFO seeks proposals for evaluation projects to inform policy and practice in the field of youth justice in the following two topics: 1. Evaluations on Juvenile Justice System Prosecution 2. Evaluations of Juvenile Reentry Practices

The goal of the NAWCA program in Canada is to promote partnerships between public agencies and groups interested in:• Protecting, improving, restoring, and managing an appropriate distribution and variety of wetland ecosystems and other habitats for wetlands-associated migratory birds and other fish and wildlife in North America;• maintaining and improving the current distribution of wetlands-associated migratory bird populations; and• sustaining an abundance of waterfowl (ducks, geese, and swans) and other populations of wetlands-associated migratory birds consistent with the objectives of the North American Waterfowl Management Plan, U.S. Shorebird Conservation Plan, Waterbird Conservation Plan for the Americas, Partners in Flight Bird Conservation Plan, and other international obligations contained in the treaties and migratory bird conventions and other agreements with Canada, Mexico, and other countries.• The program requires a minimum 1:1 non-federal match. At least 50% of the match must be from U.S. Sources. Proposals should demonstrate how the activities of partners involved in a wetland conservation project will encourage sustainable and effective programs for the long-term conservation of wetlands-associated migratory birds. The Act defines wetlands conservation projects as:• The acquisition of real property interests in lands or waters, including water rights, of a wetland ecosystem and associated habitat if the obtaining of such interest is subject to terms and conditions that will ensure that the real property will be administered for the long-term conservation...

A central goal of the BRAIN Initiative is to understand how electrical and chemical signals code information in neural circuits and give rise to sensations, thoughts, emotions and actions. While currently available technologies can provide some understanding, they may not be sufficient to accomplish this goal. For example, non-invasive technologies are low resolution and/or provide indirect measures such as blood flow, which are imprecise; invasive technologies can provide information at the level of single neurons producing the fundamental biophysical signals, but they can only be applied to tens or hundreds of neurons, out of a total number in the human brain estimated at 85 billion.Other BRAIN FOAs seek to develop novel technology (RFA-NS-17-003) or to optimize existing technology ready for in-vivo proof-of-concept testing and collection of preliminary data (RFA-NS-17-004) for recording or manipulating neural activity on a scale that is beyond what is currently possible. This FOA seeks applications for unique and innovative technologies that are in an even earlier stage of development than that sought in other FOAs, including new and untested ideas that are in the initial stages of conceptualization.In addition to experimental approaches, the support provided under this FOA might enable calculations, simulations, computational models, or other mathematical techniques for demonstrating that the signal sources and/or measurement technologies are theoretically capable of meeting the demands of large-scale recording or manipulation of circuit activity in humans or in animal....

Background The FDA Oncology Center of Excellence (OCE) aims to advance the development and regulation of oncology products for patients with cancer. The Pediatric Oncology Program and Rare Cancers Program were established to facilitate and expedite drug development for pediatric and other rare cancers. OCE’s Project Catalyst connects scientific knowledge, creative insight, and medical professionals to foster early-stage product innovation, which is particularly important to address the challenges related to product development for ultra-rare cancers. In collaboration with the National Institutes of Health (NIH) and the OCE, the Foundation for the National Institutes of Health (FNIH) recently launched the design phase of the Ultra-Rare Cancer Treatment Advancement Program (ULTRA), a new public-private partnership dedicated to accelerating the development of innovative ultra-rare cancer treatments.  For the purposes of this NOFO, the FDA OCE refers to cancers with an approximate annual incidence in the U.S. of 300 to 400 people or less as ultra-rare (a more stringent criterion compared to the threshold for a rare disease specified in the Orphan Drug Act based on a U.S. prevalence of

The purpose of this Funding Opportunity Announcement is to invite proposals for funding from established organizations interested in providing innovative hands-on, in-person manufacturing training and technical assistance to eligible small manufacturing business concerns, under the U.S. Small Business Administration's Empower to Grow Program (formerly known as 7(j) Management and Technical Assistance Program).

This NOFO will support research and evaluation of emerging technology implementation and impact for law enforcement purposes. Topics include policies, trainings, operational and staffing issues; communications strategies associated with technology implementation; and impacts of technology implementation and use on public safety and agency budgets. NIJ encourages researchers and practitioners to partner or build on existing researcher-practitioner partnerships to guide the law enforcement community on the best ways to implement technology to solve contemporary problems in policing. Applying for this funding opportunity involves a two-stage process that begins with submission of a concept paper. Based on the merits of the concept paper, NIJ may request that the applicant submit a full proposal. Applicants should not submit a full proposal unless invited. For information on the concept paper format, please see the General Purpose of the Funding section of this NOFO.

This NOFO seeks to support research and evaluation that advances the use of artificial intelligence (AI) in the criminal justice system. The goal of this NOFO is to enhance lawful decision-making and help improve its accuracy and effectiveness through AI applications supporting crime prevention, public safety, and criminal justice systems. Research should explore both the benefits and limitations of AI, addressing potential risks and downstream impacts. NIJ expects to fund studies that explore use cases in policing, corrections, courts, or other criminal justice adjacent areas to examine the suitability of using AI to solve operational problems, as well as evaluate the impacts and outcomes when integrated into criminal justice practice. Applying for this funding opportunity involves a two-stage process that begins with submission of a concept paper. Based on the merits of the concept paper, NIJ may request that the applicant submit a full proposal. Applicants should not submit a full proposal unless invited. For information on the concept paper format, please see the General Purpose of the Funding section of this NOFO.

The goal of this NOFO is to gather unique information not collected by other federal programs to gain a better understanding of the resources (e.g., services, supports) and opportunities (e.g., education, employment, housing, social participation) needed to reduce morbidity, mortality, and economic impacts and improve other long-term outcomes for people with autism or Fragile X Syndrome (FXS) across the lifespan. CDC proposes to implement three components in this NOFO.Component A: Survey to Promote Resources and Opportunities for aUtistic Teens and young adults (SPROUT) will utilize cohorts from the Study to Explore Early Development (SEED) Phases 1-3 (collected from 2007-2020), which were case-control studies of autism in children 2-5 years of age. Participants will range from about 10-25 years of age when this NOFO is awarded. SPROUT will be comprised of caregiver and self-report surveys intended to offer unique information on (1) service and support needs and the impact of co-occurring conditions on autistic people and their families and (2) the educational, transitional, social, and/or vocational needs and experiences of autistic adolescents and young adults. Information from these surveys will be used to improve the health and wellbeing of autistic people and their families. These activities are intended to provide data to inform ways to lessen individual, familial, and societal costs associated with autism, reduce morbidity and mortality, and improve health and well-being.Component B: Focus on Advancing Support and Transition with the Fragile X Online Registry With Ac...